Mentally and particularly physically straining work in midlife increased the need for hospital care in older age, reveals a new study published in the Age and Ageing journal. This was confirmed in the Finnish Longitudinal Study on Municipal Employees (FLAME),…
A Nordic comparative study indicates that of the Finnish men born in the middle of 1910´s only 24 % survived to the age of 75, whereas among the Swedish and Danish men the corresponding proportions were 49 and 42 percent.…
According to a research conducted at the University of Jyväskylä, estrogen acts as a regulator of muscle energy metabolism and muscle cell viability. Menopause leads to the cessation of ovarian estrogen production concurrent to the deterioration of muscle function. After…
Physical function and sense of autonomy are independent determinants of life-space mobility in older people. This was found in a study conducted at the Gerontology Research Center of the University of Jyväskylä. In this project, 848 older men and women…
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Researchers at the University of Jyväskylä in Finland have developed a new indicator for assessing active aging. The indicator is called the University of Jyväskylä Active Ageing Scale (UJACAS). Active ageing refers to having initiative and doing things the aging…
Strenuous occupational physical activity in midlife increases the risk of mobility limitation in old age, whereas leisure-time physical activity decreases the risk. This is found in a study which followed up 5,200 public sector employees for 28 years. The study…
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A recently published study, conducted at the Gerontology Research Center of the University of Jyväskylä, found associations between features of natural environment in the home neighborhood and physical activity of older people. “Water fronts are favorable areas for outdoor mobility…
The 9-year follow-up study in the Vitality 90+ Study showed that also in nonagenarians older age, male gender, the activities of daily living (ADL) disability and mobility disability, poor self-rated health and institutionalization increased the risk of mortality. Especially in…
Plasma cell-free DNA (cf-DNA) has recently emerged as a new biomarker of age-associated systemic inflammation and cell death. . In this study we analyzed the associations between the distinct cf-DNA species (i.e. unmethylated cf-DNA, mitochondrial DNA, RNAse P gene-coding cf-DNA,…
Research news: Circulating cell-free DNA is associated with mortality and inflammatory markers in nonagenarians: the Vitality 90+ Study. Advanced age is typically accompanied with low-grade inflammation – a phenomenon that has also been demonstrated to predict longevity in several studies.…