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In the middle-age or after it, the risk of falling ill in many chronic diseases increase. This is partly because of ageing and partly because of hormonal changes caused by menopause. Both chronic diseases and hormonal changes cause symptoms that make the quality of life of middle-aged women worse. Hormonal changes can affect coping at work even more than chronic diseases. In the middle-age the central period is the menopause. In the project the effect of the symptoms on workability and especially the effect of exercise, is studied.


Research group

Responsible researcher

Professor Clas-Håkan Nygård, clas-hakan.nygard (at), School of Heath Sciences, University of Tampere

Riitta Luoto, riitta.luoto (at), UKK-Institute for health promotion


PhD students

Reetta Heinonen, reetta.heinonen (at)

Jaana Moilanen, jaana.m.moilanen (at), The symptoms and quality of life of women in the age of menopause

Kirsi Mansikkamäki, kirsi.mansikkamaki (at), The effect of physical activity and obesity on alertness at work among middle-aged men and women


Selected publications

Riitta Luoto, Jaana Moilanen, Reetta Heinonen, Tomi Mikkola, Jani Raitanen, Eija Tomas, Katriina Ojala, Kirsi Mansikkamäki, Clas-Håkan Nygård . The effects of aerobic training on hot flushes and quality of life-A randomized controlled trial, Annals of Medicine, Early Online, 2011, 1-11


Jaana M. Moilanen, Tomi S. Mikkola, Jani A. Raitanen, Reetta H. Heinonen, Eija I Tomas, Clas-Håkan Nygård, Riitta M. Luoto. Effect of aerobic training on menopausal symptoms-A randomized controlled trial.  Menopause, 19, 6, 2012



UKK Institute, Tampere (Riitta Luoto)

Helsinki University Central Hospital (Tomi Mikkola)

Tampere University Central Hospital (Eija Tomas)

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