Estrogen Regulation of Muscle Apoptosis (ERMA-study) / Vuokko Kovanen and Eija Laakkonen Female steroid hormone mediated regulation of apoptosis as a mechanism of muscle aging and sarcopenia ERMA is a multidisciplinary study defined to reveal, how hormonal differences over the…
Globally and nationally one of the central questions at the heart of modern politics and policies is to how best support wellbeing of older people and meet their housing and care needs in the future. Housing, living environment and social…
Risk of metabolic dysfunction in middle aged women: systemic and intracrine estrogen and microRNAs as mediating factors (EsmiRs) / Eija Laakkonen Aging and specifically menopausal transition (cessation of ovarian estradiol) may greatly increase fat accumulation and the risk of several…
The project aims to combine large-scale molecular databases and develop statistical models for the assessment of pathways linking molecular information to complex phenotype expressions such as hypertension. The resulting models are applied to data from monozygotics twins of the SAWES-study…
Tampere Longitudinal Study on Aging (TamELSA) / Marja Jylhä TamELSA focuses on health and functioning, living conditions and way of life, social contacts, use of and need for services, and experiences of life among individuals aged 60 to 89 years.…
Gerontology Research Center;PO Box 35, FI-40014 University of JyväskyläStreet Address: Rautpohjankatu 8Gerontology Research CenterPO Box 100FI-33014 University of TampereStreet Address: Arvo Ylpön katu 34 FI-33520 Tampere
Aging is associated with a functional decline of the immune system, which manifests as an increased morbidity and mortality to infectious diseases and cancer. We focus on the analysis of the function and distribution of the cells of human immune…
Evergreen The purpose of this project is to describe changes in health and functioning among older people. Living conditions and life-style are studied as predictors health, functioning need of care and mortality. This multidisciplinary study includes several prospective arms. In…
Jyvaskyla Longitudinal Study of Personality and Social Development (JYLS) / Katja Kokko In the Jyväskylä Longitudinal Study of Personality and Social Development (JYLS) the development of the same individuals (born in 1959) has been followed from age 8 to 50.…
Muscle strength and power in old age: special emphasis on lower limb asymmetry, mobility and balance (Asymmetry) IRCTN34271567The aim is to study the functional consequences of lower limb muscle asymmetry to mobility, balance, falls and fear of falling of older…
The healthy ageing –sub study of the Helsinki Birth Cohort Study focuses on early life factors such as growth and development as determinants of later life health and functioning. The cohort member were born between 1934 and 1944. The register…
The retirement process of entrepreneurs: retirement plans, decision making, transition and adjustment to life in retirement (ENTREPRENEUR) In this research project, we will study the retirement process entrepreneurs and the underlying personal, organizational and societal factors that are associated with…