A new study on menopausal women shows that leisure-time physical activity is associated with a healthier blood lipid profile. However, results suggest that leisure-time physical activity does not seem to entirely offset the unfavorable lipid profile changes associated with the menopausal transition.<\/p>\n
Women experience a rapid increase in cardiovascular disease (CVD) risk after the onset of menopause. This observation suggests the presence of factors in middle-aged women that accelerate the progression of CVD independent of chronological aging.<\/p>\n
\u201cIt is well known that physical activity has health benefits, yet it is less clear to what extent physical activity can prevent the negative changes seen in blood lipid profiles during the menopausal transition,\u201d says Matthew Jergenson, MD, from the University of Minnesota Medical School, Minneapolis, Minnesota. \u201cThe present study examined menopausal women in the city of Jyv\u00e4skyl\u00e4, Finland, to explore the role of leisure-time physical activity on CVD risk factors.\u201d<\/p>\n
The present study is part of the Estrogenic Regulation of Muscle Apoptosis (ERMA) study, which examines the role of menopause on body composition, leisure-time physical activity and the risk of metabolic diseases.<\/p>\n
\u201cBased on our findings, leisure-time physical activity was associated with a healthier blood lipid profile,\u201d explains postdoctoral researcher Sira Karvinen from the Gerontology Research Center, Faculty of Sport and Health Sciences, University of Jyv\u00e4skyl\u00e4, Finland. \u201cYet advancing menopausal status predicted a less healthy lipid profile, suggesting that leisure-time physical activity does not entirely offset the unfavorable lipid profile changes associated with the menopausal transition.\u201d<\/p>\n
More specifically, higher leisure-time physical activity was associated with lower total cholesterol, LDL, triglyceride and fasting blood glucose levels as well as higher HDL levels. Advancing menopausal status, in turn, was associated with higher total cholesterol, triglyceride and LDL levels.<\/p>\n
\u201cHowever, leisure-time physical activity may attenuate the unfavorable atherogenic changes in the serum CV risk factors of healthy middle-aged women,\u201d Jergenson and Karvinen state. \u201cHence one should not forget sport-related hobbies at middle age.\u201d<\/p>\n
The present study is part of the Estrogenic Regulation of Muscle Apoptosis (ERMA) study, a population-based cohort study (n = 886) of middle-aged Caucasian women between 47 and 55 years of age in the Jyv\u00e4skyl\u00e4 area. In addition, 193 women composed a longitudinal study population that was followed over the menopausal transition. Physical activity was assessed both by self-reported questionnaires and accelerometer monitoring. Serum lipid profiles (total cholesterol, LDL, HDL, triglycerides, fasting blood glucose) were analyzed to quantify cardiovascular risk factors.<\/p>\n
The present study was carried out in collaboration between the universities of Jyv\u00e4skyl\u00e4 and Minnesota and LIKES Research Center and is part of Adjunct Professor Eija Laakkonen\u2019s Academy of Finland project.<\/p>\n
Original paper:<\/strong> Karvinen SM, Jergenson MJ, Hyv\u00e4rinen M, Aukee P, Tammelin T, Sipil\u00e4 S, Kovanen V, Kujala UM and Laakkonen EK.\u00a0Front. Endocrinol., 30 August 2019. https:\/\/doi.org\/10.3389\/fendo.2019.00589.\u00a0www.frontiersin.org\/articles\/10.3389\/fendo.2019.00589\/full<\/p>\n Contact information:
\nMenopausal Status and Physical Activity Are Independently Associated With Cardiovascular Risk Factors of Healthy Middle-Aged Women: Cross-Sectional and Longitudinal Evidence<\/p>\n
\n<\/strong>Matthew Jergenson, MD,\u00a0mjergenson@uwhealth.org,\u00a0+1 (507)-459-0951
\nwww.jyu.fi\/erma\/en<\/a><\/p>\n","protected":false,"raw":"A new study on menopausal women shows that leisure-time physical activity is associated with a healthier blood lipid profile. However, results suggest that leisure-time physical activity does not seem to entirely offset the unfavorable lipid profile changes associated with the menopausal transition.\r\n\r\nWomen experience a rapid increase in cardiovascular disease (CVD) risk after the onset of menopause. This observation suggests the presence of factors in middle-aged women that accelerate the progression of CVD independent of chronological aging.\r\n\r\n\u201cIt is well known that physical activity has health benefits, yet it is less clear to what extent physical activity can prevent the negative changes seen in blood lipid profiles during the menopausal transition,\u201d says Matthew Jergenson, MD, from the University of Minnesota Medical School, Minneapolis, Minnesota. \u201cThe present study examined menopausal women in the city of Jyv\u00e4skyl\u00e4, Finland, to explore the role of leisure-time physical activity on CVD risk factors.\u201d\r\nERMA study examines the effects of menopause<\/h3>\r\nThe present study is part of the Estrogenic Regulation of Muscle Apoptosis (ERMA) study, which examines the role of menopause on body composition, leisure-time physical activity and the risk of metabolic diseases.\r\n\r\n\u201cBased on our findings, leisure-time physical activity was associated with a healthier blood lipid profile,\u201d explains postdoctoral researcher Sira Karvinen from the Gerontology Research Center, Faculty of Sport and Health Sciences, University of Jyv\u00e4skyl\u00e4, Finland. \u201cYet advancing menopausal status predicted a less healthy lipid profile, suggesting that leisure-time physical activity does not entirely offset the unfavorable lipid profile changes associated with the menopausal transition.\u201d\r\n\r\nMore specifically, higher leisure-time physical activity was associated with lower total cholesterol, LDL, triglyceride and fasting blood glucose levels as well as higher HDL levels. Advancing menopausal status, in turn, was associated with higher total cholesterol, triglyceride and LDL levels.\r\n\r\n\u201cHowever, leisure-time physical activity may attenuate the unfavorable atherogenic changes in the serum CV risk factors of healthy middle-aged women,\u201d Jergenson and Karvinen state. \u201cHence one should not forget sport-related hobbies at middle age.\u201d\r\n\r\nThe present study is part of the Estrogenic Regulation of Muscle Apoptosis (ERMA) study, a population-based cohort study (n = 886) of middle-aged Caucasian women between 47 and 55 years of age in the Jyv\u00e4skyl\u00e4 area. In addition, 193 women composed a longitudinal study population that was followed over the menopausal transition. Physical activity was assessed both by self-reported questionnaires and accelerometer monitoring. Serum lipid profiles (total cholesterol, LDL, HDL, triglycerides, fasting blood glucose) were analyzed to quantify cardiovascular risk factors.\r\n\r\nThe present study was carried out in collaboration between the universities of Jyv\u00e4skyl\u00e4 and Minnesota and LIKES Research Center and is part of Adjunct Professor Eija Laakkonen\u2019s Academy of Finland project.\r\n\r\nOriginal paper:<\/strong>\r\nMenopausal Status and Physical Activity Are Independently Associated With Cardiovascular Risk Factors of Healthy Middle-Aged Women: Cross-Sectional and Longitudinal Evidence\r\n\r\nKarvinen SM, Jergenson MJ, Hyv\u00e4rinen M, Aukee P, Tammelin T, Sipil\u00e4 S, Kovanen V, Kujala UM and Laakkonen EK.\u00a0Front. Endocrinol., 30 August 2019. https:\/\/doi.org\/10.3389\/fendo.2019.00589.\u00a0www.frontiersin.org\/articles\/10.3389\/fendo.2019.00589\/full\r\n\r\nContact information:\r\n<\/strong>Matthew Jergenson, MD,\u00a0mjergenson@uwhealth.org,\u00a0+1 (507)-459-0951\r\nwww.jyu.fi\/erma\/en<\/a>"},"excerpt":{"rendered":"Juuri julkaistu jyv\u00e4skyl\u00e4l\u00e4isten vaihdevuosi-ik\u00e4isten naisten tutkimus osoittaa, ett\u00e4 aktiivinen vapaa-ajan liikunta on yhteydess\u00e4 parempiin veren rasva-arvoihin. Tutkimuksen perusteella liikunta ei kuitenkaan yksin riit\u00e4 est\u00e4m\u00e4\u00e4n vaihdevuosien mukanaan tuomia ep\u00e4suotuisia muutoksia veriarvoissa. Syd\u00e4n- ja verisuonitautien riskitekij\u00f6iden tason huononemisen on havaittu ajoittuvan vaihdevuosi-ik\u00e4\u00e4n,…","protected":false,"raw":""},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_mi_skip_tracking":false,"_fi_post_content":"Juuri julkaistu jyv\u00e4skyl\u00e4l\u00e4isten vaihdevuosi-ik\u00e4isten naisten tutkimus osoittaa, ett\u00e4 aktiivinen vapaa-ajan liikunta on yhteydess\u00e4 parempiin veren rasva-arvoihin. Tutkimuksen perusteella liikunta ei kuitenkaan yksin riit\u00e4 est\u00e4m\u00e4\u00e4n vaihdevuosien mukanaan tuomia ep\u00e4suotuisia muutoksia veriarvoissa.\r\n\r\nSyd\u00e4n- ja verisuonitautien riskitekij\u00f6iden tason huononemisen on havaittu ajoittuvan vaihdevuosi-ik\u00e4\u00e4n, jolloin munasarjojen estrogeenintuotanto hiipuu. T\u00e4m\u00e4n havainnon pohjalta vaihdevuosien aikana tapahtuvilla hormonaalisilla muutoksilla on ajateltu olevan omia kronologisesta i\u00e4st\u00e4 riippumattomia vaikutuksia syd\u00e4n- ja verisuonitautien esiintyvyyteen.\r\n\r\n- Vapaa-ajan liikunnalla tiedet\u00e4\u00e4n olevan terveyden kannalta edullisia vaikutuksia, mutta sit\u00e4, miss\u00e4 m\u00e4\u00e4rin liikunnalla voidaan ehk\u00e4ist\u00e4 juuri vaihdevuosiin ajoittuvia muutoksia, ei t\u00e4ysin tunneta. Tutkimuksessamme seurattiin jyv\u00e4skyl\u00e4l\u00e4isi\u00e4 vaihdevuosi-ik\u00e4isi\u00e4 naisia ja selvitettiin liikunta-aktiivisuuden merkityst\u00e4 syd\u00e4n- ja verisuonitautien riskitekij\u00f6ille, tutkijatohtori Sira Karvinen<\/strong> Jyv\u00e4skyl\u00e4n yliopiston liikuntatieteellisest\u00e4 tiedekunnasta ja Gerontologian tutkimuskeskuksesta kertoo.\r\n
ERMA-tut\u00adki\u00admus sel\u00advit\u00adt\u00e4\u00e4 laa\u00adjas\u00adti vai\u00adhe\u00advuo\u00adsien vai\u00adku\u00adtuk\u00adsia<\/h3>\r\nNyt julkaistu tutkimus on osa Estrogeeni, vaihdevuodet ja toimintakyky (ERMA) -tutkimushanketta, jossa selvitet\u00e4\u00e4n, millaisia muutoksia kehon koostumuksessa, liikuntatottumuksissa ja metabolisten sairauksien riskitekij\u00f6iss\u00e4 tapahtuu vaihdevuosien aikana.\r\n\r\n- Tutkimuksessamme havaittiin, ett\u00e4 aktiivinen vapaa-ajan liikunta oli yhteydess\u00e4 parempiin veren rasva-arvoihin. Toisaalta vaihdevuosien edetess\u00e4 rasva-arvot huononivat, joten liikunta ei yksin riitt\u00e4nyt est\u00e4m\u00e4\u00e4n vaihdevuosien mukanaan tuomia ep\u00e4suotuisia muutoksia, Karvinen kertoo.\r\n\r\nTutkimuksessa suurempi vapaa-ajan liikunnan m\u00e4\u00e4r\u00e4 oli yhteydess\u00e4 matalampiin veren kokonaiskolesteroli-, LDL-, triglyseridi- ja paastoverensokeriarvoihin ja kasvaneeseen HDL-tasoon. Toisaalta vaihdevuosien eteneminen oli yhteydess\u00e4 korkeampiin veren kokonaiskolesteroli-, triglyseridi- ja LDL-tasoihin.\r\n\r\n- Aktiivinen vapaa-ajan liikunta voi kuitenkin osaltaan lievent\u00e4\u00e4 syd\u00e4n- ja verisuonitautien riskitekij\u00f6iden tason huononemista terveill\u00e4 vaihdevuosi-ik\u00e4isill\u00e4 naisilla, joten liikunnallisia harrastuksia ei kannata keski-i\u00e4ss\u00e4k\u00e4\u00e4n unohtaa, Karvinen muistuttaa.\r\n\r\nT\u00e4ss\u00e4 tutkimuksessa hy\u00f6dynnettiin ERMA-tutkimuksen aineistoa, johon osallistui 886 keski-ik\u00e4ist\u00e4 naista (47\u201355 vuotta) Jyv\u00e4skyl\u00e4n alueelta. Lis\u00e4ksi 193 naista muodosti pitkitt\u00e4isaineiston, jota seurattiin menopaussivaiheen yli. Liikunta-aktiivisuuden mittaamiseen k\u00e4ytettiin tutkittavien itseraportointia sek\u00e4 kiihtyvyysantureilla tehtyj\u00e4 mittauksia. Veren rasva-arvoja (kokonaiskolesteroli, LDL, HDL, triglyseridit, paastoverensokeri) k\u00e4ytettiin kuvaamaan syd\u00e4n- ja verisuonitautien riski\u00e4.\r\n\r\nTutkimus toteutettiin yhteisty\u00f6n\u00e4 Jyv\u00e4skyl\u00e4n yliopiston, Minnesotan yliopiston ja LIKES-tutkimuskeskuksen kanssa osana dosentti Eija Laakkosen<\/strong> johtamaa akatemiatutkijan projektia.\r\n\r\n\r\nAlkuper\u00e4inen artikkeli:\r\n<\/strong>Menopausal Status and Physical Activity Are Independently Associated With Cardiovascular Risk Factors of Healthy Middle-Aged Women: Cross-Sectional and Longitudinal Evidence\r\n\r\nKarvinen SM, Jergenson MJ, Hyv\u00e4rinen M, Aukee P, Tammelin T, Sipil\u00e4S, Kovanen V, Kujala UM and Laakkonen EK. Front. Endocrinol., 30 August 2019. https:\/\/doi.org\/10.3389\/fendo.2019.00589. Linkki julkaisuun: https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2019.00589\/full\r\n\r\n\r\nLis\u00e4tietoja:\r\n<\/strong>Tutkijatohtori Sira Karvinen, sira.karvinen@jyu.fi, 0503625120\r\nwww.jyu.fi\/erma<\/a>","_fi_post_name":"liikunnalla-voi-lieventaa-vaihdevuosiin-liittyvia-muutoksia-sydan-ja-verisuonitautien-ris","_fi_post_excerpt":"","_fi_post_title":"Lii\u00adkun\u00adnal\u00adla voi lie\u00adven\u00adt\u00e4\u00e4 vaih\u00adde\u00advuo\u00adsiin liit\u00adty\u00advi\u00e4 muu\u00adtok\u00adsia sy\u00add\u00e4n- ja ve\u00adri\u00adsuo\u00adni\u00adtau\u00adtien ris\u00adki\u00adteki\u00adj\u00f6is\u00ads\u00e4","_en_post_content":"A new study on menopausal women shows that leisure-time physical activity is associated with a healthier blood lipid profile. However, results suggest that leisure-time physical activity does not seem to entirely offset the unfavorable lipid profile changes associated with the menopausal transition.\r\n\r\nWomen experience a rapid increase in cardiovascular disease (CVD) risk after the onset of menopause. This observation suggests the presence of factors in middle-aged women that accelerate the progression of CVD independent of chronological aging.\r\n\r\n\u201cIt is well known that physical activity has health benefits, yet it is less clear to what extent physical activity can prevent the negative changes seen in blood lipid profiles during the menopausal transition,\u201d says Matthew Jergenson, MD, from the University of Minnesota Medical School, Minneapolis, Minnesota. \u201cThe present study examined menopausal women in the city of Jyv\u00e4skyl\u00e4, Finland, to explore the role of leisure-time physical activity on CVD risk factors.\u201d\r\n
ERMA study examines the effects of menopause<\/h3>\r\nThe present study is part of the Estrogenic Regulation of Muscle Apoptosis (ERMA) study, which examines the role of menopause on body composition, leisure-time physical activity and the risk of metabolic diseases.\r\n\r\n\u201cBased on our findings, leisure-time physical activity was associated with a healthier blood lipid profile,\u201d explains postdoctoral researcher Sira Karvinen from the Gerontology Research Center, Faculty of Sport and Health Sciences, University of Jyv\u00e4skyl\u00e4, Finland. \u201cYet advancing menopausal status predicted a less healthy lipid profile, suggesting that leisure-time physical activity does not entirely offset the unfavorable lipid profile changes associated with the menopausal transition.\u201d\r\n\r\nMore specifically, higher leisure-time physical activity was associated with lower total cholesterol, LDL, triglyceride and fasting blood glucose levels as well as higher HDL levels. Advancing menopausal status, in turn, was associated with higher total cholesterol, triglyceride and LDL levels.\r\n\r\n\u201cHowever, leisure-time physical activity may attenuate the unfavorable atherogenic changes in the serum CV risk factors of healthy middle-aged women,\u201d Jergenson and Karvinen state. \u201cHence one should not forget sport-related hobbies at middle age.\u201d\r\n\r\nThe present study is part of the Estrogenic Regulation of Muscle Apoptosis (ERMA) study, a population-based cohort study (n = 886) of middle-aged Caucasian women between 47 and 55 years of age in the Jyv\u00e4skyl\u00e4 area. In addition, 193 women composed a longitudinal study population that was followed over the menopausal transition. Physical activity was assessed both by self-reported questionnaires and accelerometer monitoring. Serum lipid profiles (total cholesterol, LDL, HDL, triglycerides, fasting blood glucose) were analyzed to quantify cardiovascular risk factors.\r\n\r\nThe present study was carried out in collaboration between the universities of Jyv\u00e4skyl\u00e4 and Minnesota and LIKES Research Center and is part of Adjunct Professor Eija Laakkonen\u2019s Academy of Finland project.\r\n\r\nOriginal paper:<\/strong>\r\nMenopausal Status and Physical Activity Are Independently Associated With Cardiovascular Risk Factors of Healthy Middle-Aged Women: Cross-Sectional and Longitudinal Evidence\r\n\r\nKarvinen SM, Jergenson MJ, Hyv\u00e4rinen M, Aukee P, Tammelin T, Sipil\u00e4 S, Kovanen V, Kujala UM and Laakkonen EK.\u00a0Front. Endocrinol., 30 August 2019. https:\/\/doi.org\/10.3389\/fendo.2019.00589.\u00a0www.frontiersin.org\/articles\/10.3389\/fendo.2019.00589\/full\r\n\r\nContact information:\r\n<\/strong>Matthew Jergenson, MD,\u00a0mjergenson@uwhealth.org,\u00a0+1 (507)-459-0951\r\nwww.jyu.fi\/erma\/en<\/a>","_en_post_name":"physical-activity-may-attenuate-menopause-associated-atherogenic-changes","_en_post_excerpt":"","_en_post_title":"Physical activity may attenuate menopause-associated atherogenic changes","edit_language":"en","footnotes":""},"categories":[130],"tags":[224,222,155,154,223,218,179,221,220,219],"class_list":["post-7028","post","type-post","status-publish","format-standard","hentry","category-tiedeuutiset","tag-cardiovascular-disease","tag-erma","tag-fyysinen-aktiivisuus","tag-liikunta","tag-menopause","tag-menopaussi","tag-physical-activity","tag-sira-karvinen","tag-sydan-ja-verisuonitaudit","tag-vaihdevuodet","entry","no-media"],"_links":{"self":[{"href":"https:\/\/www.gerec.fi\/en\/wp-json\/wp\/v2\/posts\/7028","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.gerec.fi\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.gerec.fi\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.gerec.fi\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.gerec.fi\/en\/wp-json\/wp\/v2\/comments?post=7028"}],"version-history":[{"count":2,"href":"https:\/\/www.gerec.fi\/en\/wp-json\/wp\/v2\/posts\/7028\/revisions"}],"predecessor-version":[{"id":7030,"href":"https:\/\/www.gerec.fi\/en\/wp-json\/wp\/v2\/posts\/7028\/revisions\/7030"}],"wp:attachment":[{"href":"https:\/\/www.gerec.fi\/en\/wp-json\/wp\/v2\/media?parent=7028"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.gerec.fi\/en\/wp-json\/wp\/v2\/categories?post=7028"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.gerec.fi\/en\/wp-json\/wp\/v2\/tags?post=7028"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}